Synthesis of silica nanoparticles incorporating triazolyl macrocycle

Incorporating of silica nanoparticles with crown ethers is interest regarding the excellent stability these inorganic polymers against various acidic and basic conditions. The attachments to macrocycles are involved many reactions attach active site ether modified nanoparticles. To achieve goal, selection 3,5-dihydroxybenzolic acid as a model for synthesis macrocycle base reaction esterification residue followed by etherification propargyl chloride finally cyclization di azide form 4. From other side, nanoparticle both magnetic mesoporous were prepared in different size properties according literature. final step involving attachment type, two methods used. First method was included crafting ready synthesized under medium. Second one-pot adding 4, directly before finish reaction. All compounds have been characterized instrumental techniques include FT-IR, 1H NMR, 13C EXD, XRD, FESEM, TEM BET.